New data have been uploaded. Please check out the 'Data Download' page. The data are gene expression profiles generated by Agilent 44k Whole Human Genome Microarray. Control genes are removed from the datasets. Experiments include measuring expression change of THP-1 cells treated with LPS/Ado/LA for 3h, Feverfew for 24h, Feverfew for 3h, Ganoderma for 24h, and Arnica for 24h compared with corresponding controls. Experimental detail available upon request.

The project gaol of Chen Lab has been updated. Please click on 'Projects' for details.

Feverfew may be a potential drug for cancer. In 2/16's lab meeting we discussed the relationship between feverfew extracs SFE/SRE/DeWE/Mex and major ingredients Volitile Oil/Parthenolide. Please think about the possible solution for our experiment results.

The following is a good tutorial website for real time RT-PCR. Please give it a read before designing and conducting your experiment. http://pathmicro.med.sc.edu/pcr/realtime-home.htm

The goal of our laboratory is to utilize a combination of molecular biology, Systems biology, microarrys, proteomics, and bioinformatics approaches to study the signaling pathways in human macrophages. In particular we are focusing on understanding the mechanisms that mediate pro/anti- inflammation and host-pathogen interaction.

Welcome to Chen Lab. Registration in not required for submmiting an article. However, registration is recommended for full functionality on this website. Please click on "Contribute" on top banner of the page to compose your article. If you're not a registered user, your articles will be reviewed by one of our administrators before posting. We welcome your opions and contribution of articles. For non-registered users, the article you submitted will be shown on the page as soon as we review it. Please send the email to ccheng@clemson.edu to report any problems for using this system.